Software and Instructions to Access and Download These Colorado Divorce & Mediation Tools & Forms. To download the FREE Adobe. Feb 24, 2012. Graphical user interface (GUI), a high level of software automation, and free availability for commercial and noncommercial use. FEATURES AND THEORETICAL BACKGROUND. KinetDS is software for curve fitting, designed particularly to describe the cumulative dissolution curve by a simple equation.

Most recently, we have developed a powerful software, named DDSolver, for estimating drug dissolution/release similarity. The software is free to all.

You can download it from the Spriger's website providing you have the right to access the fulltext of the Springer Database. DDSolver is a freely available program which is capable of performing most existing techniques for comparing drug release data, including exploratory data analysis, univariate ANOVA, ratio test procedures, the difference factor f 1, the similarity factor f 2, the Rescigno indices, the 90% confidence interval (CI) of difference method, the multivariate statistical distance method, the model-dependent method, the bootstrap f 2 method, and Chow and Ki’s time series method. The DDSolver software is available at the Electronic Supplementary Materials page of the paper's website. In addition, a detailed disscusion of the approaches for estimating similarity between dissolution profiles was supplied as Supplementary File. Important Note: To install DDSolver on your computer, you should first change the _9185_MOESM2_ESM.xls downloaded from the Springer's website into _9185_MOESM2_ESM.xla, then everything will go smoothly as directed in Installation Structions Document. It is a little bug of Springer's website, we are contacting Springer for fixing this bug. Our published article introducing the DDSolver is: DOI:10.1208/s12248-010-9185-1 The AAPS Journal, 2010 DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles Yong Zhang, Meirong Huo, Jianping Zhou, Aifeng Zou, Weize Li, Chengli Yao and Shaofei Xie (1) Department of Pharmaceutics, China Pharmaceutical University, No.

24, Tongjiaxiang, 210009 Nanjing, China (2) Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Center for Instrumental Analysis, China Pharmaceutical University, No.24, Tongjiaxiang, 210009 Nanjing, China To locate this article, you can google it by using 'DDSolver' as a keyword. It's easy to find it. Last edited by ZhangYong; at 10:57 AM. It is a very useful software. But I have some (two) problem with using of it. In case of model fitting, after pushing the run button, an error message appear (microsoft visual basic: run-time error '13' type mismatch), and the fitting is not fulfilled, only empty charts are listed.

Yeni Hitit 2 Free Download Pdf there. An other error message appear in other cases: microsoft visual basic: run-time error '1004' Range category NumberFormatLocal can not be set, but the calulation is fulfilled. Maybe is it the problem of excel settings? Do you have any suggestion to solve these problems? Dear ZhangYong, The problem has been solved. The regional options of windows was not compatible with the software.Thanks for your valuable feedback providing a possible solution to this problem. Dear ZhangYong Thank you very very much for your excellent work.

It is a very useful software and very good research. I used your software and rad your paper. But there are some point in Parameters for characterizing drug release curve: mk, moments of dissolution times of order k, what is the meaning of it?

And what is the value of K? RD, relative dispersion of dissolution time, in some paper they conclude the release mechanism from it how they do that? ABC, area between the drug dissolution curve and its asymptote, what is asymptote? MDT, mean dissolution time, some paprers calculate dissolution rate from MDT, Kd=1/MDT, is that right? Thank you for this software, I have found it quite useful and easy to master. I recently encountered a few 'problems'?

I am trying to characterize the mechanism of release of some new drugs using the Korsmeyer-Peppas equation. The R2 value improves when I use the equation with lag time 'F = kKP*(t-Tlag)^n' compared to when I use the equation without the lag time 'F = kKP*t^n'. Can I choose the model with lag time since it fits better? In addition, to characterize release mechanism using the Korsmeyer-Peppas model, only 60% or less of release data can be incorporated. Some of my new drugs reach beyond 60% dissolution by the second sampling point, making it difficult to apply this - the software requires at least 4 time points.

Is there any other way I can address this?

Click Here To Download: • • WinSOTAX Advanced Dissolution Software is a 21 CFR Part 11 compliant, validated on Windows XP/2000 software package that controls each of our automated dissolution systems as well as our spectrophotometers. SOTAX partners with THERMO ELECTRON to sell and support the Evolution 300 spectrophotometer. Convert Pdf Indesign Cs3 Tutorial Free. WinSOTAX Advanced Dissolution Software has convenient handling as users see only menus and dialogs which conform to their hardware configuration and user rights. WinSOTAX has on-line modules for UV/VIS spectrophotometric measurements, cell grouping function multiple tests and virtual dilution, interface for pH measurements and protocolling, and protocol of rpm, temperature, pH including statistical functions min./max., mean and standard deviation.